There is a state-of-the-art medical institution known as "The Cube." Catherine Black, neurologist, works in this "Cube," doing her best to figure out exactly what it is that makes the brain work and how to help those whose brains, perhaps, aren't working as well as they would like. She also, not to give too much away (it is right their in the official synopsis, so we're not), is bipolar, so there's a whole "physician heal thyself" sort of thing going on. The show follows her and other docs/staff members doing their thing on a weekly basis. Said others also include actress Vanessa Redgrave.