Sandra Bullock and Melissa McCarthy already have a box office hit on their hands with the new comedy "The Heat" (besting "White House Down," which pairs Channing Tatum and Jamie Foxx), and the chemistry between the two stars is the film's biggest selling point. We decided it was a good time to take a look at some of Hollywood's best buddy comedies from the past, starring such noted pairings as Oscar & Felix, Wayne & Garth, Romy & Michelle, Buzz & Woody, and many more.
Check out our picks here. Do you agree or disagree with our choices? What did we miss?
Plus: After reading the gallery story, vote in our poll for your no. 1 buddy movie below.