"Hedwig and the Angry Inch" talk at a "Smurfs 2" press junket? Why not?

Neil Patrick Harris was clearly eager to talk about the forthcoming Broadway production during our recent sit-down about the family-oriented sequel, and his enthusiasm for taking on the title role - that of a transgendered rock singer living in East Berlin - came through in a pretty big way.

"I saw 'Hedwig and the Angry Inch' when it was at the Jane Street Playhouse...gosh, twenty years ago or something," Harris told me of his first exposure to John Cameron Mitchell's acclaimed Off-Broadway production, which became the basis for the 2001 film of the same name. "And I thought it was so bold. And it turned out that they wanted to do it on Broadway and we started having a conversation. I wasn't able to do it because 'How I Met Your Mother' was going on, so they would continue to sort of call and say, you know, 'what about this hiatus?' And I was like, 'I can't. I don't have time to do it.'"

Of course, now that "How I Met Your Mother" is entering its final season, the actor finally has the freedom to take the challenge on.

"It's gonna be super fun," he gushed. "I'm gonna have to change my whole body type and lose some weight, lose some mass and probably you know, shave in weird places, tuck. Walk around in heels. But as a career move I thought it was a smart call too. You know, Barney's such an alpha male, mainstream guy and I thought how interesting for people to see me in my next move, it's sort of a right turn. Seemingly shocking...but then when you go see the show it's a really moving show, there's some really just like...[it's] very dramatic. And so I think it'll be fun to do drama and, like, be Ziggy Stardust for a minute."

Click on the video above for the full clip.

"Hedwig and the Angry Inch" is slated to premiere on Broadway next spring.

A former contributor to sites including MTV's The Backlot and Bloody-Disgusting, Chris Eggertsen worked in film development before indulging his love of pop culture writing full time. He specializes in horror, the intersection of social issues and entertainment and Howard Stern. He's on Twitter @HitFixChris.