"Neighbors" partied hard at the box office on Friday, earning a huge $19.6 million and unseating "Amazing Spider-Man 2" from the top spot.

The raunchy comedy, starring Seth Rogen and Zac Efron, is on its way to a weekend debut just under $50 million. It's a great start for a film that reportedly cost just $18 million to produce.

"Spider-Man," which features returning stars Andrew Garfield and Emma Stone, swung to No. 2 with $10.1 million on Friday. It will likely earn around $36 million for the weekend, putting it within reach of a $150 million domestic total.

The Sony sequel has so far earned a big $340 million overseas. It also stars Jamie Foxx, Paul Giamatti and Dane DeHaan.

The Cameron Diaz comedy "The Other Woman" scored another $2.8 million for third place on Friday, bringing its domestic total to a strong $55.2 million.

The Christian-themed drama "Heaven is For Real" earned $1.6 million. Its domestic total stands at an impressive $69.8 million.

Long-term champ "Captain America: The Winter Soldier" rounded out the top five, picking up another $1.4 million. The Marvel sequel has so far earned a huge $240.8 million.

The new faith-based comedy "Mom's Night Out," debuted in sixth place, nabbing $1.2 million. The Patricia Heaton comedy will likely earn around $5 million for the weekend. 

Next week's big openers include Warner Bros.' new "Godzilla" and the Jon Hamm baseball drama "Million Dollar Arm."

Look for continuing box office updates throughout the weekend on HitFix.