Mathematician John Nash and his wife Alicia, subjects of the Oscar-winning 2001 film "A Beautiful Mind," were killed in a New Jersey automobile accident Sunday. They were 86 and 82 respectively.

The car reportedly crashed into the guard rail, and the couple was ejected from the vehicle. They were pronounced dead at the scene.

The Nashes were portrayed by Russell Crowe and Jennifer Connelly in Ron Howard's film. Connelly won the Best Supporting Actress Oscar while the film also won Best Picture, Best Director and Best Adapted Screenplay.

"This is a great loss," Connelly said in a statement. "John and Alicia Nash were an inspiration and I have deep admiration for all that they accomplished in their lives. My thoughts are with their family."

Nash is renowned for his work in game theory. He won the Nobel Prize for Economics in 1994. He also struggled with schizophrenia, which became the focus of the largely dramatized film.

Kristopher Tapley has covered the film awards landscape for over a decade. He founded In Contention in 2005. His work has also appeared in The New York Times, The Times of London and Variety. He begs you not to take any of this too seriously.