Looking back at the most defining moments of Otto Octavious' career as Spider-Man
1. Anna Maria Marconi (First appearance: "Superior Spider-Man" #5)
It may be shocking that a one-time villain has done so much to help a society that once completely rejected him, but the element that humanized Otto Octavius' Spider-Man the most was the woman he gave his heart to. Ock was never a romantic figure; he was a pudgy nerd with a Moe Howard haircut. Not a dashing or handsome man, he was often ridiculed, particularly by Peter, for his appearance. Perhaps this is part of the reason why when he came across the object of his affections, Ock looked beneath the surface to find true love.
Anna Maria Marconi is a brilliant scientist, a gourmet chef, a woman who possesses a true heart, and a woman who maintains a steely strong resolve in the face of ridicule. Anna also happens to be a little person, and Ock not only loves her, he seems wonderfully oblivious to this fact. The addition of Anna to the cast allowed Ock to find a depth beyond any he ever had in his arch-villain days.
Ock saw Anna for the inspiring figure she is, which caused the reader to see Ock as more than a villain. The idea of a villain in the body of an iconic hero is a bit difficult for a reader to wrap their heads around for over thirty issues, but thanks to his blossoming relationship with Anna, we found ourselves rooting for him, even if that meant we'd never see Peter Parker again. For Anna's sake! Otto's affections for his girlfriend showed his amazing depth and the heart of a man who can look past the superficial. Peter's love interests included sexy cat burglars, super models and other beauties, which begs the question: When he is once again in control of his body and life, what happens to Anna?