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Nominated for: Best Supporting Actress, Bridesmaids
2011 marked the beginning of Melissa McCarthy's ascent into the celebrity stratosphere. She scored an Emmy win for Mike & Molly and landed a lovably vulgar role in Bridesmaids, playing the dog-loving, air marshal-seducing Megan. Was she hilarious? Certainly. But the role is such an atypical Oscar candidate thanks to its bawdy dialogue ("I'm glad he's single because I'm going to climb [him] like a tree") and relentless weirdness.