Eric Stonestreet leads a category in which all six 2010 nominees return
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Jeremy Piven of 'Entourage'
Jeremy Piven, "Entourage"
Nomination Status: Never rule out a three-time winner.
In His Favor: For a long time, Jeremy Piven was as sure a thing as this category had to offer, with four nominations and three wins between 2005 and 2008. He hasn't been nominated the past two years, so he's gone from favorite to longshot, but his name still has to be mentioned, if only as a cautionary tale.
Working Against Him: The bloom is off the "Entourage" rose. Perhaps next summer "Entourage" might get a little Emmy comeback to honor its final season, but that won't come this year.