Glenn Close is the two-time champ, but can she hold off a good wife?
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Julianna Margulies of 'The Good Wife'
Julianna Margulies, "The Good Wife"
Nomination Status: A lock for a nomination and very possibly the favorite.
In Her Favor: Julianna Margulies isn't just the star of one of the year's breakout drama hits, she's a commanding star, anchoring nearly every scene of the well-regarded drama. It's a nuanced performance and it has already earned Margulies a Golden Globe win. Factor in Margulies' history at the Emmys -- six nominations, including one win for "E.R." -- and the expectation that "The Good Wife" will potentially be an Outstanding Drama Series player and you have a star who could end Glenn Close's reign.
Working Against Her: None to speak of. Magulies is well liked and well respected.