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Melissa McCarthy ("St. Vincent")
Pros: McCarthy's breakthrough role in "Bridesmaids" also earned her an Oscar nomination in this same category. The Emmy Award winner is very good as a struggling mom trying to keep it together in Theodore Melfi's dramedy.
Cons: Will "St. Vincent" be a big enough hit for The Weinstein Company to seriously campaign it? Is the industry effectively "over" McCarthy after the painful "Tammy" this past summer?
- Gregory Ellwood