Just who exactly are these A-holes?
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Origin allusion: Of an unnamed species, Nebula is one of many children adopted by Thanos. She has numerous cybernetic alterations, whether from torture at the hands of her "father" or some unknown calamity is never broached...though her statement of "Look what my father did to me," implies Thanos is responsible for her state either way. Nebula suffers from jealousy of her "sister" Gamora who is Thanos's favorite daughter and it drives many of her actions throughout the movie.
But wait: According to comic book Nebula, she is the blood granddaughter of Thanos, not his adopted child. She doesn't even meet her alleged grandfather until well into her illustrious space pirate career. This changes everything. There is no jealousy of Gamora spurring her on, as the two do not meet until years later. There are no involuntary cybernetic enhancements. In their stead is her starship where she captains a crew of 10,000 with ruthless calculation and voluntary cyborg implants that give her the edge in a brutal line of work. Her list of crimes include destroying Xander, attempted conquering of the Skrull empire, and stealing the Infinity Gauntlet.
So what now? Luckily because of the hazy nature of timelines in Marvel movies, most of Nebula's impressive story arc could still come to pass. Nothing is stopping her from becoming the most feared space pirate in the galaxy. Or from reconciling with her "sister" Gamora and fighting alongside a bevy of warrior women. It all depends on what path to character development Marvel wants to go down. There's even room for Nebula to be the entry point for a Guardians/Captain Marvel cross-over as she is the first person to come in contact with Monica Rambeau (or Carol Danvers in MCU most likely).