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12. Sarah Silverman
First things first, Sarah Silverman gave us my choice for the single greatest one-liner of all time: "When life gives you AIDS, make lemonAIDS." But she's also a defiant provocateur whose droll and weird sense of humor belies steadfast conscientiousness. If "Jesus is Magic" didn't sell you on her wild righteousness, her fantastic "Sarah Silverman Program" and book "The Bedwetter" will do the trick. And best of all, she's f*cking Matt Damon.
- Chris Eggertsen