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Melissa McCarthy, "Bridesmaids"
Pro: To say McCarthy stole the show in last summer's monster surprise hit is an understatement. She arguably received more of a career boost than leading lady Kristen Wiig and the love for her work in the Paul Fieg comedy is credited for her shocking Emmy Award win for best actress in a comedy ("Mike & Molly") in September. The Academy rarely recognizes comedic performances, especially by women. However, Whoopi Goldberg in "Ghost," Penelope Cruz in "Vicky Christina Barcelona," Marisa Tomei in "My Cousin Vinny," Diane Wiest and Jennifer Tilly in "Bullets Over Broadway," Sigourney Weaver and Joan Cusack in "Working Girl" and Olympia Dukakis in "Moonstruck" prove if it's gonna happen, it'll happen in best supporting.
Con: It's a very broad comedic role. If there was a bit more dramatic heft to the part she'd be a lock. Still, the people's champion has a legitimate shot. Maybe.