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He considers 'Avengers' star Mark Ruffalo to be the 'definitive' Bruce Banner
@Teh_Bear: "Did losing Edward Norton in any way damage your vision for the avengers?"
@IAMAJossWhedon: "It let me cast Mark Ruffalo, one of the best and sweetest actors I know, and, I think, THE definitive Bruce Banner. (Apologies to Mr. Bixby.)"
Note: Ok, so he probably had to say that.