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Gnarls Barkley - 'Crazy'
Innovative producer/DJ Danger Mouse and Goodie Mob frontman (and future "The Voice" coach) Cee Lo Green teamed for this funky, infectious oddity that seemingly came out of nowhere and appeared to be destined to be the ultimate jam of 2006. It danced around for seven weeks at No. 2 while Nelly Furtado's already forgotten "Promiscuous" prevented the Barkley Boys from reaching the top spot.