Each new show will be paired with an established comedy, as ABC has also moved "Scrubs" and "Samantha Who?" to new slots.
"Better Off Ted," a workplace comedy starring Jay Harrington, Portia de Rossi, Andrea Anders and Jonathan Slavin, will premiere on Wednesday, March 18 at 8:30 p.m. ET, following "Scrubs," which will be transplanted to Wednesday in the 8 p.m. time slot.
Meanwhile, on Thursdays, "Ugly Betty" will take a break, opening up the Thursday night 8 p.m. hour for "In the Motherhood" and the Emmy nominated "Samantha Who." ABC's new Thursday comedy block will premiere on March 26 and "Ugly Betty" will return when the two shows complete their runs.
"In the Motherhood" stars Megan Mullally and Cheryl Hines and looks at a group of friends dealing with the trials and tribulations of motherhood.
The "Samantha Who?" move follows last week's announcement that this new installment of "The Bachelor" will air in two-hour blocks for the duration of its run, leading into "True Beauty."